Sonata for sale

RODUCT DESCRIPTION

Sonata (a medication that induces sleep) that is used for treating insomnia. It is chemically unrelated to the benzodiazepine class of medications for sleep, for Sonata for sale example, lorazepam (Ativan), oxazepam (Serax), flurazepam (Dalmane), triazolam (Halcion), and temazepam (Restoril), but it has similar effects because it attaches to the same receptors on nerve cells as these well-known medications. It was approved by the FDA in 1999.Sonata for sale

Zaleplon is used for the short-term treatment of insomnia. It decreases the time to the onset of sleep and was used for up to 5-weeks in clinical trials. It does not increase total sleep time or decrease the number of awakenings.Sonata for sale

DOSAGE METHOD

For the short-term (generally 7 to 10 days) treatment of insomnia.

Oral dosage

Adults

10 mg PO at bedtime. May take either at bedtime or after an attempt to fall asleep without medication, provided at least 4 or more hours of sleep time remain. For certain debilitated, low weight patients, patients with hepatic insufficiency, or those on medications that reduce zaleplon clearance, use 5 mg PO initially. A 20 mg PO bedtime dose may be considered for the occasional patient who does not benefit from 10 mg at bedtime.

Geriatric Adults

5 mg PO at bedtime. Max: 10 mg/day, if necessary. Zaleplon may be taken either at bedtime or after an attempt to fall asleep without medication, provided at least 4 or more hours of sleep time remain. The federal Omnibus Budget Reconciliation Act (OBRA) regulates the use of sedative/hypnotics in long-term care facility (LTCF) residents. Max: 5 mg/day PO in residents meeting the criteria for treatment, except when documentation is provided showing that higher doses are necessary to maintain or improve the resident’s functional status. All sleep medications should be used in accordance with approved product labeling. If the sleep agent is used routinely and is beyond the manufacturer’s recommendations for duration of use, the facility should attempt a quarterly taper unless clinically contraindicated as defined in the OBRA guidelines.

Which drugs or supplements interact with zaleplon?

Rifampin reduces the amount of zaleplon in the blood by more than 80%. This could lead to a decrease in zaleplon’s activity. Cimetidine (Tagamet) can increase the amount of zaleplon in the blood by 85% by reducing the breakdown of zaleplon in the liver. If cimetidine must be used, lower doses of zaleplon are suggested. Ketoconazole (Nizoral, Extina, Xolegel, Kuric), erythromycin and similar drugs that reduce breakdown of drugs in the liver also increase blood concentrations of zaleplon. The drowsiness that can occur with zaleplon is accentuated by alcohol, and, therefore, patients taking zaleplon should not drink alcoholic beverages. Imipramine (Tofranil, Tofranil-PM) and thioridazine also increase drowsiness when combined with zaleplon.

NEGATIVE EFFECTS

The most common side effects associated with zaleplon are:

headache,

drowsiness,

dizziness,

amnesia,

stomach ache, and

muscle pain.

Studies have shown that zaleplon has a potential for abuse similar to benzodiazepines. Patients may experience rebound insomnia on the first night after stopping zaleplon. Zaleplon can cause abnormal behavior or thinking or “complex sleep-related behaviors,” which may include sleep-driving (driving with no memory of having done so). If these side effects occur, zaleplon should be discontinued.